The phrase “overdose” sometimes brings unlawful medication to thoughts. However it’s not solely avenue medication or the abuse of prescription medicines that may overwhelm the physique and trigger injury or dying. Substances which can be thought of innocent and even wholesome can change into toxic when misused.
The objects listed under vary from benign to helpful in small quantities however change into poisonous in increased portions. These seemingly innocent substances can land you within the hospital—or the morgue—if you happen to overdo it.
10 Soy Sauce
In 2013, a 19-year-old man from Virginia drank zero.9 liters (1 qt) of soy sauce after being dared by his associates to take action. He went right into a coma and practically died from the acute ranges of salt in his physique.
Hypernatremia is a situation in which there’s an excessive amount of salt within the blood. When the bloodstream turns into saturated with salt, it attracts water from different elements of the physique, together with the mind, in an try and decrease the salt focus. When the mind loses water, it will possibly shrink and bleed.
After the Virginia teen drank the soy sauce, he started having seizures. His associates introduced him to the hospital, however by the point he arrived, he had already fallen right into a coma. Medical doctors flushed the salt from his system utilizing a mixture of water and sugar dextrose.
His sodium ranges returned to regular 5 hours later, however he remained within the coma for 3 days earlier than waking up on his personal. Medical doctors stated that the younger man was fortunate to be alive. He’s the primary individual to overdose on such a excessive quantity of salt and survive with none lasting neurological issues.[1]
9 Tea
An Arkansas man suffered kidney failure on account of consuming an excessive amount of iced tea.
The 56-year-old man drank about 16 240-milliliter (8 oz) cups of iced tea each day. In Could 2014, the person was admitted to the hospital after complaining of nausea, weak point, and physique aches. Medical doctors found that his kidneys have been extraordinarily clogged and irritated. They began him on dialysis, which he’ll most likely be on for the remainder of his life.
The injury to the person’s kidneys was brought on by a chemical known as oxalate. This chemical happens naturally in black tea in addition to different meals corresponding to rhubarb and spinach. An excessive amount of oxalate can result in kidney injury.[2] The person from Arkansas was consuming 3–10 occasions extra oxalate than the common American.
In keeping with the Harvard College of Public Well being, consuming as much as four cups of tea per day is a secure quantity. Sixteen cups per day is just too many.
8 Nutmeg
Nutmeg is in style this time of yr, however ensure to not sprinkle an excessive amount of on prime of your eggnog. Ingesting as little as roughly 4.4 grams (2 tsp) of the spice may end up in nutmeg toxicity.
Normally, individuals who ingest giant quantities of nutmeg are in search of a excessive. The spice incorporates a pure compound known as myristicin, which has hallucinogenic results in giant doses which can be just like the excessive from LSD.
Utilizing the spice as a drug is a apply in style with youngsters and jail inmates due to its accessibility. However although nutmeg is authorized and simple to acquire, there are some very disagreeable negative effects of ingesting the quantity required to expertise a excessive.
Inside an hour of consuming a considerable amount of nutmeg, customers sometimes endure extreme gastrointestinal issues. After a number of extra hours, individuals can start experiencing coronary heart and nerve issues. That is particularly harmful for anybody with an undiagnosed coronary heart drawback.
Hallucinations don’t happen till a number of hours after ingesting nutmeg, which might lead individuals to devour further quantities in the event that they assume they didn’t take sufficient the primary time.
Utilizing the spice as a drug shouldn’t be a contemporary growth. Widespread nutmeg intoxication instances have been seen within the early 1900s after which once more within the 1960s earlier than resurfacing extra lately.[3]
7 Toothpaste
An excessive amount of toothpaste can have tragic outcomes. Within the early 1990s, toothpaste labels contained primary warnings that stated, “Do Not Swallow. Use solely a pea-sized quantity for kids below six.”
The Meals and Drug Administration (FDA) didn’t imagine that these cautions addressed the true risks of consuming toothpaste. So in 1997, a poison warning was added to toothpaste merchandise that contained fluoride.
The American Dental Affiliation in addition to toothpaste producers thought that this requirement was an overreaction by the FDA. Nevertheless, the FDA argued that fluoride is a drug related to toxicity and, due to this fact, requires a powerful warning for shoppers.
Whether or not or not the warnings are too extreme, consuming toothpaste shouldn’t be a good suggestion. Swallowing a considerable amount of fluoride-free toothpaste will seemingly lead to nothing greater than an upset abdomen. Nevertheless, swallowing a considerable amount of toothpaste containing fluoride may be deadly.
Kids are extra inclined to fluoride poisoning as a result of their smaller our bodies are affected by smaller quantities of the substance. A single tube of youngsters’s fluoride toothpaste incorporates sufficient fluoride to kill a baby weighing lower than 30 kilograms (66 lb). If a baby have been to ingest solely 3 p.c of the tube, he would nonetheless expertise acute fluoride poisoning, which causes flu-like signs, dizziness, and gastric ache.[4]
6 Cruciferous Greens
Cruciferous greens are a household of nutrient-rich, leafy inexperienced crops corresponding to broccoli, Brussels sprouts, and kale. These veggies are sometimes beneficial as a result of they include excessive ranges of antioxidants and different well being advantages, however consuming too many leafy greens can have damaging outcomes.
In 2011, a person was hospitalized after overdosing on Brussels sprouts at Christmas dinner. The person had a mechanical coronary heart and was taking anticoagulants. Like most cruciferous greens, Brussels sprouts include excessive quantities of vitamin Okay, which promotes blood clotting. The anticoagulants have been needed for the person’s mechanical coronary heart to function successfully.[5]
When an excessive amount of vitamin Okay counteracted the results of the person’s medicine, he started experiencing sudden coronary heart issues. As soon as medical doctors realized that the issues have been as a result of man consuming too many Brussels sprouts, they have been capable of deal with him. Fortuitously, he recovered rapidly.
Consuming an excessive amount of broccoli or kale also can lead to hypothyroidism (an underactive thyroid) the place the thyroid gland fails to make sufficient thyroid hormone. Dietary specialists say that “cheap quantities” of cruciferous greens provide many well being advantages. The damaging results of consuming too many leafy greens solely occur when individuals devour excessive doses. As soon as an individual is identified with hypothyroidism, they’re warned to keep away from cruciferous greens.
5 Star Fruit
Carambola (aka star fruit) can do some main hurt contained in the physique if an excessive amount of is consumed. For individuals who have already got weak kidneys, kidney injury or failure can happen from consuming only a small quantity.
Star fruit incorporates a toxin that’s able to wreaking havoc on the renal system. Individuals with wholesome kidneys can sometimes filter the toxin with no unwell results, however anybody with present kidney injury is warned in opposition to consuming star fruit.[6]
The fruit is very harmful for people who find themselves unaware that they’ve early phases of kidney injury. Along with individuals who have present kidney issues, those that eat the fruit regularly or drink star fruit juice on an empty abdomen are at highest threat for star fruit toxicity.
Signs of star fruit toxicity embrace nausea, weak point, insomnia, seizures, and hiccups, that are the commonest symptom in delicate instances. Medical doctors can deal with extreme instances of star fruit toxicity with dialysis, however kidney perform could by no means return to regular after the injury happens.
4 Tuna
Warnings about consuming tuna are typically directed at pregnant girls and babies, however the remainder of us are additionally in danger if we overdo it on the sushi bar.
Uncooked, cooked, and canned tuna all include mercury. Mercury is present in most sorts of fish, however greater predatory fish include increased concentrations. Tuna eat smaller fish, so additionally they devour the mercury content material of smaller fish, which raises their mercury degree.
Mercury is poisonous to people. Small quantities may be filtered out, however bigger quantities will construct up and lead to mercury poisoning. The earliest indicators of poisoning embrace poor coordination and numbness within the fingers and toes, adopted by tremors and imaginative and prescient issues. Lengthy-term mercury poisoning can have an effect on reminiscence perform and impair the training course of. Extreme instances may end up in kidney issues, respiratory failure, and dying.
Many individuals are conscious of the risks of consuming an excessive amount of tuna however are unaware of the particular quantity that’s “an excessive amount of.” Sure sorts of tuna, corresponding to the favored albacore, include increased ranges of mercury.
For an individual weighing 68 kilograms (150 lb) or extra, the FDA recommends consuming no a couple of 170-gram (6 oz) can of albacore tuna each 9 days. Which means an every-other-day behavior of tuna on rye for lunch would simply be sufficient to trigger mercury poisoning.[7]
3 Muscle Cream
Muscle cream can present aid from aches and pains, however utilizing an excessive amount of can have deadly penalties.
Methyl salicylate is an anti-inflammatory present in merchandise that soothe sore muscle groups, corresponding to Bengay and Icy Scorching. Although muscle cream is utilized topically, the substance enters the physique by way of the pores and permeates muscle groups and nerves in addition to the bloodstream.
In 2007, Arielle Newman died from an unintentional overdose of methyl salicylate.[8] The 17-year-old monitor star recurrently used muscle cream in addition to adhesive pads containing methyl salicylate.
Newman’s overdose was a results of repeated purposes of excessive portions. Her physique absorbed the methyl salicylate over time till the chemical reached poisonous ranges.
She additionally utilized muscle cream earlier than taking part in a monitor meet, which is believed to have been an extra consider Newman’s dying. The warmth that was generated as she ran would have opened her pores, inflicting elevated absorption.
2 Black Licorice
Black licorice may be harmful, particularly for individuals over age 40. The FDA launched a report earlier this yr cautioning in opposition to the results of consuming black licorice regularly or in giant portions. The warning from the FDA got here after a 2016 case the place somebody who usually consumed black licorice skilled coronary heart issues that have been attributed to the chewy sweet.
Consuming simply 57 grams (2 oz) of black licorice, which is about three 2.5-centimeter (1 in) items, each day for 2 weeks could cause coronary heart issues. Black licorice incorporates glycyrrhizin, a compound that causes potassium ranges to lower. When potassium ranges fall, persons are vulnerable to affected by irregular coronary heart rhythms, hypertension, and even congestive coronary heart failure.
Individuals with present coronary heart issues are at increased threat of experiencing an antagonistic impact from consuming black licorice.[9]
1 Nutritional vitamins
Nutritional vitamins are supposed to enhance our well being, however taking too many dietary supplements can really trigger cancers properly as different well being issues.
Some sorts of nutritional vitamins are water-soluble. Extra ranges of water-soluble nutritional vitamins get flushed out by way of urine. However different nutritional vitamins, corresponding to vitamin A, are lipid-soluble. These kind of nutritional vitamins are saved in physique fats and don’t get flushed out the identical method. Lipid-soluble nutritional vitamins can construct as much as poisonous ranges and trigger liver injury, beginning defects, central nervous system issues, and most cancers.
In 1985, a bunch of medical doctors started a trial by which individuals took excessive doses of beta-carotene, a vitamin A complement that was believed to cut back the chance of getting most cancers. The trial was shut down early as a result of the routine backfired and induced most cancers in a number of the individuals as an alternative of stopping it. Particularly, male people who smoke who took beta-carotene dietary supplements have been 18 p.c extra more likely to develop lung most cancers than those that didn’t.[10]
A 2001 examine carried out by the Nationwide Most cancers Institute resulted in an identical final result. The examine assessed the effectiveness of vitamin E in stopping prostate most cancers. The findings confirmed that males who took vitamin E dietary supplements have been really 17 p.c extra more likely to develop prostate most cancers than those that didn’t.
Water-soluble nutritional vitamins corresponding to vitamin C are sometimes flushed from the physique earlier than toxicity happens, however there can nonetheless be damaging results from excessive doses. Overdoing it on vitamin C may end up in diarrhea, abdomen cramps, and even kidney stones.
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